Proof of Usefulness Report

PostEra

Analysis completed on 1/28/2026

+605
Proof of Usefulness Score
Category Standard

PostEra is a highly significant biotechnology company (YC W20) verified to have raised over $26M (Series A) and established a major AI Lab partnership with Pfizer. The company led the global 'COVID Moonshot' open-science initiative, demonstrating immense real-world utility. Although the specific user submission contained low-quality, exaggerated placeholder text (e.g., claiming 'most people' have used the product), independent verification confirms exceptional traction, technical innovation in ML-driven retrosynthesis, and strong market relevance.

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Score Breakdown

Real World Utility+178.13
Audience Reach Impact+70.00
Technical Innovation+103.50
Evidence Of Traction+178.13
Market Timing Relevance+45.00
Functional Completeness+1.25
Subtotal+576.01
Usefulness Multiplierx1.05
Final Score+605

Project Details

Project URL
Description
PostEra is a biotechnology company backed by YCombinator (YC W20).\n\nDrug discovery R\u0026D is slow and expensive and this limits biotechs and pharma from getting new drugs into development and new cures to patients. PostEra is building a one-stop-shop for medicinal chemistry, powered by machine learning, to serve the world's ever expanding community of drug hunters while also leading the world's largest open-science initiative to find a COVID cure; COVID Moonshot.\n\nPostEra offers 2 products:\n\n1. Partnerships - We offer our full stack of machine learning tools to help our partners (small biotech to large pharma) develop drugs faster and cheaper.\n\n2. Manifold - We offer a cloud based platform where drug hunters can use our ML tools to reduce the time and cost of their drug discovery.\n\nAs a company we have a particular of focus on chemical synthesis; the process of making molecules and Manifold's flagship product centers on solving this problem of how to get compounds made.

Algorithm Insights

Market Position
Strong market validation with clear user adoption patterns
User Engagement
Documented reach suggests active user community
Technical Stack
Modern tech stack aligned with sponsor technologies

Recommendations to Increase Usefulness Score

Document User Growth

Provide specific metrics on user acquisition and retention rates

Showcase Revenue Model

Detail sustainable monetization strategy and current revenue streams

Expand Evidence Base

Include testimonials, case studies, and third-party validation

Technical Roadmap

Share development milestones and feature completion timeline