Proof of Usefulness Report

Nanosene Ltd.

Analysis completed on 2/8/2026

+70
Proof of Usefulness Score
You're In Business

Nanosene is a verified spinout from Stellenbosch University developing BzAM polymers for membrane protein solubilization, a critical tool in drug discovery. While the core technology and technical innovation are scientifically sound and patent-backed with commercial partners (e.g., Cube Biotech), the submission quality is critically poor. It contains verifiable falsehoods (claiming 'most people have used my product' and 'everyone' as the audience) and ambiguous financial data ('marketcap: 2500000'). The project scores high on innovation and utility but is heavily penalized for reach, traction claims, and response quality, placing it in the 'Minimal traction' (<50k users) calibration bucket typical for early-stage niche B2B biotech.

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Score Breakdown

Real World Utility0.25)
Audience Reach Impact0.20)
Technical Innovation0.15)
Evidence Of Traction0.25)
Market Timing Relevance0.10)
Functional Completeness0.05)
Subtotal+60.63
Usefulness Multiplierx1.15
Final Score+70

Project Details

Project URL
Description
For researchers and drug developers to create and discover new therapeutics to treat diseases such as obesity, depression or even cancer, they need to study and understand proteins embedded in the cell membrane. These membrane proteins (MPs) play an essential role in regulating physiological processes, therefore considered prime therapeutic targets for nearly 70% of FDA-approved drugs. Nanosene’s technology produces polymers that act as indispensable tools for the solubilization of fully intact and functional MPs in nanoscale discs. This nanodisc technology offers researchers the unprecedented opportunity to access some of the most valued proteins in a biologically active state.

Algorithm Insights

Market Position
Growing utility with room for optimization
User Engagement
Documented reach suggests active user community
Technical Stack
Modern tech stack aligned with sponsor technologies

Recommendations to Increase Usefulness Score

Document User Growth

Provide specific metrics on user acquisition and retention rates

Showcase Revenue Model

Detail sustainable monetization strategy and current revenue streams

Expand Evidence Base

Include testimonials, case studies, and third-party validation

Technical Roadmap

Share development milestones and feature completion timeline